Dr. Greenthumb’s, the cannabis dispensary chain founded by Cypress Hill rapper B Real, launches its sixth location in La Mesa, California, on October 2. This marks the brand’s first entry into San Diego County, expanding its footprint from Sylmar origins to major cities across the state. The grand opening promises a daylong event blending community festivities, high-end cannabis offerings, and cultural tributes to B Real’s heritage.
From Rap Legacy to Retail Empire
B Real established Dr. Greenthumb’s in 2018, drawing on his stature as a cannabis activist and Cypress Hill frontman to build a retailer focused on premium products. The chain stocks flowers and extracts from cultivators like Insane, Alien Labs, CAM, Cannabiotix, and Wonderbrett, which appeal to discerning consumers seeking potent, flavorful strains. Starting in Sylmar, the brand grew rapidly, adding outposts in Cathedral City, downtown Los Angeles, San Francisco, and Sacramento, with a seventh site near LAX in the works. This expansion reflects California’s maturing legal cannabis market, where quality and brand loyalty drive competition among hundreds of dispensaries.
Grand Opening Honors Community Roots
The La Mesa site at 8760 Campo Rd. hosts its celebration from 9 a.m. to 9 p.m., open to all adults 21 and older. B Real appears from 1 p.m. to 4 p.m., joining activations that include on-site murals by graffiti artists Strive One and MEX, cannabis vendors, food trucks, giveaways, and lowriders in the parking lot. A Latin theme underscores B Real’s Mexican and Cuban background, featuring George Lopez’s Chingon Bakery with pan dulce and tamales, plus unmedicated churros from Big Pete’s edibles. “I’m so excited to bring the Dr. Greenthumb’s experience to San Diego,” B Real said. “The community here loves high-quality cannabis and I feel honored not only to be able to deliver top-shelf product, but to celebrate the community that has shaped who I am.”
Cultural Celebration Amid Broader Revival
B Real frames the event as a post-pandemic gathering, emphasizing safe reconnection after last year’s disruptions. “After all of the uncertainty of last year and the terrible effects it had on the community, I want to bring everyone together safely for a day of celebration,” he added. This approach ties into cannabis culture’s evolution from underground scenes to mainstream retail, where dispensaries serve as social hubs. In San Diego County, the debut signals potential for further growth, as legal sales statewide topped $5 billion annually by recent measures, fostering jobs and tax revenue while normalizing consumption spaces.